{"id":77,"date":"2023-05-22T09:06:07","date_gmt":"2023-05-22T09:06:07","guid":{"rendered":"https:\/\/sites.exeter.ac.uk\/ironoverload\/?page_id=77"},"modified":"2024-12-12T10:38:14","modified_gmt":"2024-12-12T10:38:14","slug":"home","status":"publish","type":"page","link":"https:\/\/sites.exeter.ac.uk\/ironoverload\/","title":{"rendered":"Welcome"},"content":{"rendered":"\n<p>On this site <a href=\"https:\/\/sites.exeter.ac.uk\/ironoverload\/who-are-we\/\" data-type=\"page\" data-id=\"745\">we<\/a> aim to provide the most accurate information to help patients with <em>HFE<\/em> gene variants understand their risk of haemochromatosis, using data from the <a href=\"https:\/\/www.ukbiobank.ac.uk\/\">UK Biobank<\/a> study of 500,000 adults aged 40 to 70 years in the United Kingdom.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><strong>Haemochromatosis <\/strong>is one of the most common genetic diseases affecting patients of northern European ancestry. It is overdiagnosed in patients without iron overload and is underdiagnosed in many patients.<\/p>\n<cite><a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(23)00287-8\" data-type=\"URL\" data-id=\"https:\/\/doi.org\/10.1016\/S0140-6736(23)00287-8\">Professor Paul Adams <em>et al.<\/em> (2023) <em>Lancet<\/em><\/a><\/cite><\/blockquote>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/sites.exeter.ac.uk\/ironoverload\/what-is-haemochromatosis\/\">What is genetic haemochromatosis?<\/a><\/div>\n<\/div>\n\n\n\n<p><\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-font-size\" style=\"font-size:24px\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/sites.exeter.ac.uk\/ironoverload\/patient-reports\/\"><strong>What is my risk of haemochromatosis, based on my genotype?<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<p><\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/sites.exeter.ac.uk\/ironoverload\/other-risk-factors\/\">What factors other than <em>HFE <\/em>genotype affect my risk?<\/a><\/div>\n<\/div>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>On this site we aim to provide the most accurate information to help patients with HFE gene variants understand their risk of haemochromatosis, using data from the UK Biobank study of 500,000 adults aged 40 to 70 years in the United Kingdom. Haemochromatosis is one of the most common genetic diseases affecting patients of northern [&hellip;]<\/p>\n","protected":false},"author":293,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Welcome - Haemochromatosis: genetic iron overload disease<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.exeter.ac.uk\/ironoverload\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Welcome - Haemochromatosis: genetic iron overload disease\" \/>\n<meta property=\"og:description\" content=\"On this site we aim to provide the most accurate information to help patients with HFE gene variants understand their risk of haemochromatosis, using data from the UK Biobank study of 500,000 adults aged 40 to 70 years in the United Kingdom. Haemochromatosis is one of the most common genetic diseases affecting patients of northern [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.exeter.ac.uk\/ironoverload\/\" \/>\n<meta property=\"og:site_name\" content=\"Haemochromatosis: genetic iron overload disease\" \/>\n<meta property=\"article:modified_time\" content=\"2024-12-12T10:38:14+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sites.exeter.ac.uk\/ironoverload\/\",\"url\":\"https:\/\/sites.exeter.ac.uk\/ironoverload\/\",\"name\":\"Welcome - Haemochromatosis: genetic iron overload disease\",\"isPartOf\":{\"@id\":\"https:\/\/sites.exeter.ac.uk\/ironoverload\/#website\"},\"datePublished\":\"2023-05-22T09:06:07+00:00\",\"dateModified\":\"2024-12-12T10:38:14+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/sites.exeter.ac.uk\/ironoverload\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/sites.exeter.ac.uk\/ironoverload\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/sites.exeter.ac.uk\/ironoverload\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/sites.exeter.ac.uk\/ironoverload\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Welcome\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/sites.exeter.ac.uk\/ironoverload\/#website\",\"url\":\"https:\/\/sites.exeter.ac.uk\/ironoverload\/\",\"name\":\"Haemochromatosis: genetic iron overload disease\",\"description\":\"Summary for patients\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/sites.exeter.ac.uk\/ironoverload\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Welcome - Haemochromatosis: genetic iron overload disease","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sites.exeter.ac.uk\/ironoverload\/","og_locale":"en_US","og_type":"article","og_title":"Welcome - Haemochromatosis: genetic iron overload disease","og_description":"On this site we aim to provide the most accurate information to help patients with HFE gene variants understand their risk of haemochromatosis, using data from the UK Biobank study of 500,000 adults aged 40 to 70 years in the United Kingdom. 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