Multi-layered bacterial genome defences

Publications, impact and outreach

We are excited to share the outputs from our research with a wide audience! Check back to this page regularly to find links to publications, impact and outreach. You can also reach out to us via our contact page or follow us on @multidefence.bsky.social.

Publications

Multi-layered genome defences in bacteria in Current Opinion in Microbiology, Volume 78 (2024). https://doi.org/10.1016/j.mib.2024.102436

Went, S. C., et al. “Structure and Rational Engineering of the PglX Methyltransferase and Specificity Factor for BREX Phage Defence.” Nature Communications, vol. 15, 2024, article no. 7236, https://doi.org/10.1038/s41467-024-51629-7

Harrington, N. E., et al. “Global Genomic Diversity of Pseudomonas Aeruginosa in Bronchiectasis.” Journal of Infection, vol. 89, no. 5, 2024, article 106275, https://doi.org/10.1016/j.jinf.2024.106275

Dimitriu, Tatiana, et al. “Various Plasmid Strategies Limit the Effect of Bacterial Restriction–Modification Systems Against Conjugation.” Nucleic Acids Research, vol. 52, no. 21, 27 Nov. 2024, pp. 12976–12986, https://doi.org/10.1093/nar/gkae896

Maestri, Alice, et al. “The Bacterial Defense System MADS Interacts with CRISPR-Cas to Limit Phage Infection and Escape.” Cell Host & Microbe, vol. 32, no. 8, 2024, pp. 1412–1426.e11, https://doi.org/10.1016/j.chom.2024.07.005

Alseth, E. O., et al. “The Impact of Phage and Phage Resistance on Microbial Community Dynamics.” PLOS Biology, vol. 22, no. 4, 2024, article e3002346, https://doi.org/10.1371/journal.pbio.3002346