Haemochromatosis: genetic iron overload disease

Haemochromatosis: genetic iron overload disease

Summary for patients

Patient Reports

The biggest predictor of haemochromatosis is genetic variants in the HFE gene (see What is haemochromatosis?). Risk in each individual is affected by many factors, including age, sex, alcohol, diet, and genetic ancestry (see Risk modifiers).

Click below to find out your risk of haemochromatosis based on your HFE genotype.

C282Y homozygote
(i.e., two copies)
C282Y heterozygote
(i.e., one copy)

H63D homozygote
(i.e., two copies)
H63D heterozygote
(i.e., one copy)

C282Y / H63D compound heterozygote
(i.e., one copy of each variant)

No copies of C282Y or H63D