Haemochromatosis: genetic iron overload disease
Summary for patients
Haemochromatosis: genetic iron overload disease
Summary for patients
Welcome to our haemochromatosis-related publications page. Here, you will find a list of our research articles published from 2019 onwards.
Banfield et al (2026) Radiographically identified vertebral fractures in haemochromatosis-associated HFE C282Y homozygotes in the UK Biobank. MedRxiv. doi: 10.64898/2026.08.19.26360796
Agarvas et al (2026). Ferritin and transferrin predict common carotid intima-media thickness in females: a machine-learning informed individual participant data meta-analysis. BMC Cardiovascular Disorders. 26(1):360. doi: 10.1186/s12872-026-05796-8
Arede et al (2026). Loss of HFE impairs hematopoietic stem and progenitor cell function. Blood Red Cells & Iron. 2(2). doi: 10.1016/j.brci.2026.100061
Parker et al (2026). An association between haemochromatosis genotypes and venous leg ulcers in Australian individuals. Wound Repair and Regeneration. Wound Repair and Regeneration. 34:e70127.34:e70127. doi: 10.1111/wrr.70127
Lucas et al (2026). Genetic and lifestyle modifiers of haemochromatosis-related clinical outcomes in HFE C282Y homozygotes. JHEP Reports. doi: 10.1016/j.jhepr.2026.101781
Lucas et al (2026). Liver iron levels are associated with HFE-hemochromatosis genotype, diet, adiposity, and disease in the UK Biobank. Hepatol Commun. doi: 10.1097/hc9.0000000000000883
Banfield LR et al (2026). Chondrocalcinosis and the haemochromatosis linked HFE C282Y homozygous variant in the UK Biobank. EULAR Rheumatology Open. 2(1):1-8. doi: 10.1016/j.ero.2025.11.016
Agarvas et al (2025). Iron biomarkers predict peripheral artery disease in females. Atherosclerosis. 402: 119111. doi: 10.1016/j.atherosclerosis.2025.119111
Lucas et al (2025) Incidence of liver complications with hemochromatosis associated HFE p.C282Y homozygosity: The role of central adiposity Hepatology. 81(5): 1522-1534. doi: 10.1097/HEP.0000000000001056
Lucas et al (2024) HFE genotypes, haemochromatosis diagnosis and clinical outcomes at age 80 years: a prospective cohort study in the UK Biobank BMJ Open. 14(3):e081926. doi: 10.1136/bmjopen-2023-081926
Banfield et al (2023) Haemochromatosis genetic variants and musculoskeletal outcomes: 11.5 year follow-up in the UK Biobank cohort study JBMR Plus. 7(10):e10794. doi: 10.1002/jbm4.10794
Atkins et al (2023) Letter to the editor regarding: “A haemochromatosis-causing HFE mutation is associated with SARS-CoV-2 susceptibility in the Czech population” Clin Chim Acta. 542:117271. doi: 10.1016/j.cca.2023.117271
Atkins et al (2022) Hereditary Hemochromatosis Variant Associations with Incident Nonliver Malignancies: 11-Year Follow-up in UK Biobank Cancer Epidemiol Biomarkers Prev. 31(9):1780-1787. doi: 10.1158/1055-9965.EPI-22-0284
Pilling et al (2022) Genetic modifiers of penetrance to liver endpoints in HFE hemochromatosis: Associations in a large community cohort Hepatology. 76(6):1735-1745. doi: 10.1002/hep.32575
Atkins et al (2021) Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort J Alzheimers Dis 79(3):1203-1211. doi: 10.3233/JAD-201080
Atkins et al (2020) Association of Hemochromatosis HFE p.C282Y Homozygosity With Hepatic Malignancy JAMA. 324(20):2048-2057. doi: 10.1001/jama.2020.21566
Pilling et al (2019) Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank BMJ. 16;364:k5222. doi: 10.1136/bmj.k5222
Tamosauskaite et al (2019) Hereditary Hemochromatosis Associations with Frailty, Sarcopenia and Chronic Pain: Evidence from 200,975 Older UK Biobank Participants J Gerontol A Biol Sci Med Sci. 74(3):337-342. doi: 10.1093/gerona/gly270